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In this situation, transparency is essential, says Richard Sharp, Ph.

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Patients should always be informed about potential situations that might prompt an advance directive to be restricted or temporarily revoked. Home Login Join.

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Advancing the Science Mayo Clinic Medical Science Blog — an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic. Share this:. In many states, women can expect pregnancy to restrict their advance directives.

Both tests use samples from amniocentesis or chorionic villus sampling, invasive procedures that carry a small risk of miscarriage. That percentage was higher in fetuses with an abnormal ultrasound. In an editorial accompanying the paper, Lorraine Dugoff , associate professor of obstetrics and gynecology at the University of Pennsylvania Perelman School of Medicine, suggests that the new technology should be offered to women who have an abnormal ultrasound.

Pregnant pause. No prenatal care, and now she's 'bleeding like crazy'.

That makes it difficult for clinicians to interpret the results for parents who may use the information to terminate the pregnancy. The microarrays used in prenatal testing are much more limited, detecting a smaller set of CNVs, than those used in children, for precisely this reason. For example, a duplication or deletion on chromosome 16 called 16p The number of these uncertain CNVs is falling as researchers learn more about them. Wapner says that over the past five years, their proportion has dropped from 2. Researchers hope to shrink that number even further with an effort to catalog this information, the International Standards for Cytogenomic Arrays Consortium.

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They found that chunks of DNA from chromosomes 6 and 8 had been swapped, an unprecedented genetic variation that is not detectable by karyotype or microarray. By joining the discussion, you agree to our privacy policy. Spectrum: Autism Research News.